Should I Take An Estrogen Blocker With Testosterone

When To Use Estrogen Blocker With TRT

Many men experience the sensation of “slowing down” as they age. This occurs in large part due to dwindling levels of testosterone, a sex hormone responsible for things like sexual function, muscle building, bone growth, and sperm production. As testosterone production begins to decline with age, you may experience unwanted symptoms like low sex drive, erectile dysfunction, low muscle mass, weight gain, depression, irritability, and fatigue.

While aging is a completely natural process, modern medical advancements can positively influence our overall well-being at any age. Testosterone replacement therapy (TRT), like the one offered at LaSara Medical Group, can help regulate testosterone levels in your body.

In addition to low testosterone levels, an elevated level of another hormone, estrogen, could play a part in unwanted symptoms. Learn if taking an estrogen blocker in addition to your testosterone replacement therapy could be the right step for your overall wellness.

What Is Testosterone?

Several hormones play an essential role in the male body. One of these hormones, testosterone, is produced in the testicles and is essential for the following functions:

  • Erectile function
  • Correction of low libido
  • Sexual health
  • Muscle building
  • Mood stabilising
  • Energy production

When a person experiences low t (testosterone) levels, their quality of life may be adversely affected.

What is Estrogen?

Estrogen is a sex hormone that plays a vital role in male sexual health and reproductive systems and is present in the testicles. Estrogen levels in men can vary depending on their age and medical history. Typically, a man’s estradiol level is around 10-40 picograms per millimeter (pg/ml), and the estrone level is 10-50 pg/ml.

Estrogen is responsible for:

  • Maintenance and growth of bones
  • The location and distribution of body fat
  • Coordination of head and eye movement to support vision
  • Sexual functioning, such as libido and proper erectile functioning
  • Sperm creation

Is Estrogen Good or Bad for Men?

Healthy hormone levels of estrogen in men are not a problem. But when the hormonal balance is disrupted, and the male body begins producing too much estrogen, you may notice some unpleasant side effects like:

  • Gynecomastia — male breast growth or development of excess breast tissue.
  • Erectile dysfunction
  • Reduced sex drive
  • Infertility
  • Reduced muscle mass and energy
  • Hot flashes
  • Decreased testicle size
  • Low-energy fractures (where bone fractures occur due to falling from a standing height or less)What is Estrogen

Estrogen levels tend to rise for men undergoing TRT, which may require including estrogen blockers as part of your treatment plan. Not all men undergoing hormone replacement therapy will need estrogen blockers as part of their treatment. The knowledgeable medical staff at La Sara Medical Group can help formulate a customized hormone replacement therapy based on the individual patient’s blood tests and symptoms.

The Relationship Between Testosterone And Estrogen In Men

Both men and women produce testosterone and estrogen hormones. Men create more testosterone (the male hormone), and women generally make more estrogen (the female hormone). In the male body, a process called aromatization uses the enzyme aromatase to convert testosterone into an estrogen called estradiol.

Testosterone Replacement Therapy adds testosterone to the body, which, in some cases, can also correspond with heightened estrogen production. A common symptom of heightened estradiol production in men is edema – a retention of fluids in the arms and legs that cause swelling and pain. Age and obesity increase the risk of estrogen and its estradiol production overabundance. Aromatase inhibitors or estrogen blockers for men can counteract this and allow you to realize all of the benefits of TRT without the downsides.

What Are Estrogen Blockers?

Estrogen blocker medications were developed and FDA-approved for use in women suffering from breast cancer. However, these estrogen blockers can also be used off-label in males with elevated estrogen levels.

Estrogen blockers could reduce the excess estrogen production associated with testosterone therapy and allow you to receive optimal results from TRT.

Medications Used for Estrogen Blocking

Medications used as estrogen blockers include:

  • Aromatase inhibitors (AI): Aromatase inhibitors can help increase testosterone levels, along with other hormones, by inhibiting the ability of androgens to be converted to estradiol in the body. Medications in this group include anastrazole and letrozole.
  • Selective estrogen receptor modulators (SERM): SERMs bind to estrogen receptors to prevent them from binding to each other. Tamoxifen and clomiphene citrate are common SERM medications used to address the hormonal balance in males.

Side Effects of Estrogen Blockers

Estrogen blockers are generally well-tolerated. However, there aren’t FDA-established guidelines for their use in males. The following are some of the side effects of specific estrogen blocker medications:

  • AI: AI is generally well-tolerated. However, side effects may include nausea, an increase in liver enzymes, hot flashes, and headaches.
  • SERM: Clomiphene citrate usually has minimal side effects and can increase testosterone levels and improve bone mineral density and androgen deficiencies. Rare side effects include headaches, changes in vision, and gynecomastia (enlargement of male breasts). Tamoxifen has more serious side effects, like gastrointestinal upset, risk of blood clots, and cardiovascular problems.

TRT at LaSara Medical Group

If you are interested in finding out if estrogen blockers could be a beneficial addition to your TRT protocol, our helpful medical staff is here to help. At LaSara Medical Group, we understand the unique challenges men and women face. Our highest priority is to help you get back to feeling healthy and confident, and we are happy to offer nationwide coverage. Book a consultation with us today and allow us to guide you toward your goals. Our knowledgeable providers are here to help craft a personalized approach to your hormone treatment protocol and help you achieve your desired results without ever having to come into the office physically. Call us today to schedule a Telehealth appointment, or come to see us in person at one of our offices in Orange County, San Diego, or Los Angeles.